METHODS FOR SELECTION OF AGE-APPROPRIATE TISSUES

摘要

Methods of producing tissue matrices are provided. The methods can comprise selection of collagen-based tissues from animals based on desired mechanical and/or biologic properties relating to the age of a source animal. Furthermore, tissue matrices produced from animals including pigs selected at various ages to control mechanical properties are provided.

主权项

1. A method for producing a tissue product, comprising:
identifying an anatomical site for treatment; identifying a species of animal having a collagen-based tissue for use in treating the anatomical site; identifying a desired set of mechanical properties suitable for treating the anatomical site; selecting an animal of the identified species of an age at which a processed collagen-based tissue from the animal will comprise the desire set of mechanical properties; procuring a collagen-based tissue from the selected animal; and processing the collagen-based tissue to produce an acellular tissue matrix from the collagen-based tissue.