发明名称 |
MODIFIED ANTIMIR-138 OLIGONUCLEOTIDES |
摘要 |
Disclosed is a modified oligonucleotide capable of reducing or inhibiting one or more activities miR-138. The modified oligonucleotide may comprise at least one locked nucleic acid (LNA) and wherein the oligonucleotide is substantially complementary to a nucleotide sequence of miR-138. Also disclosed are pharmaceutical compositions comprising the oligonucleotides, methods of using the oligonucleotides and uses thereof. |
申请公布号 |
WO2016018193(A1) |
申请公布日期 |
2016.02.04 |
申请号 |
WO2015SG50245 |
申请日期 |
2015.07.31 |
申请人 |
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH |
发明人 |
SAMPATH, PRABHA |
分类号 |
C12N15/113;A61K31/7088;A61P35/00 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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