发明名称 COMPOSITIONS AND METHODS FOR TREATING ALLERGIC CONDITIONS
摘要 Compositions and methods are provided herein for treatment of allergic conditions, by administration of an adjuvant composition, with or without allergen.
申请公布号 US2016030459(A1) 申请公布日期 2016.02.04
申请号 US201514600593 申请日期 2015.01.20
申请人 IMMUNE DESIGN CORP. 发明人 Reed Steven G.;Clegg Christopher H.;Arendt Christopher;Kropotova Alexandra;Stoeckli Kurt
分类号 A61K31/7016 主分类号 A61K31/7016
代理机构 代理人
主权项 1. A method of treating a mammal who suffers from an allergic condition, comprising (a) administering one, two, three or four doses of a composition comprising GLA administered, optionally once weekly, for a first treatment period, followed by a rest period, followed by (b) administering a maintenance dose of an effective amount of a composition comprising GLA, and wherein the rest period between step (a) and (b) is between at least 4 weeks and 12 months; said composition comprising (a) GLA of the formula (Ia): or a pharmaceutically acceptable salt thereof, where: R1, R3, R5 and R6 are C11-C20 alkyl; and R2 and R4 are C12-C20 alkyl; and (b) a pharmaceutically acceptable carrier or excipient.
地址 Seattle WA US