发明名称 TUMOR TREATMENT METHOD FOR BLOCKING TUMOR VASCULATURE BY MEANS OF NANOMATERIAL AND EXTERNAL RADIATION SOURCE
摘要 Provided is an application of a nanomaterial to the preparation of a tumor vasculature blocking agent, said nanomaterial having all of the following properties: (1) the surface is hydrophilic; (2) the surface has electronegativity; (3) the size of the nanomaterial is 50-250 nm, and the material is rigid, such that it is not prone to passing through the hole in the wall of a tumor vessel and becoming stuck in said hole; (4) the nanomaterial can absorb external radiation energy, and internally convert same to thermal energy, and accumulate said thermal energy, causing the morphological structure of said nanomaterial to change dramatically. During treatment, the described nanomaterial is injected into a tumor-bearing organism, then radiation is applied to the tumor section, causing the nanomaterial to absorb the radiation energy and its internal temperature to rise rapidly; when the temperature has risen to a certain level, the morphological structure of the nanomaterial changes (explosion or dramatic volume expansion), thereby causing the morphological structure or function of the tumor vascular endothelial cells to change, destroying the tumor vasculature.
申请公布号 WO2016015173(A1) 申请公布日期 2016.02.04
申请号 WO2014CN00723 申请日期 2014.07.29
申请人 BEIJING FULLCAN BIO-TECHNOLOGY CO., LTD. 发明人 WANG, CHUNRU;ZHEN, MINGMING;WANG, TAISHAN;SHU, CHUNYING;ZHANG, GUOQIANG;ZOU, TOUJUN
分类号 A61P35/00;A61K47/02 主分类号 A61P35/00
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