发明名称 |
Method for providing vascular system in biological tissue |
摘要 |
A method for providing a vascular system in biological tissue in vitro, the method comprising cocultivation of the biological tissue with vascular cells and mesenchymal cells. Biological tissue in which a vascular system has been provided by said method. A method for producing a tissue or organ, the method comprising transplantation of the biological tissue in a non-human animal and inducing differentiation to a tissue or organ in which a vascular network has been constructed. A tissue or organ regeneration or function-restoring method comprising transplantation of the biological tissue in a human or non-human animal and inducing differentiation to a tissue or organ in which a vascular network has been constructed. A method for producing a non-human chimera animal, the method comprising transplantation of the biological tissue to a non-human animal and inducing differentiation to a tissue or organ in which a vascular network has been constructed. A method for evaluating drugs using at least one selected from a group consisting of the biological tissue, tissues and organs produced by said method, and non-human chimera animals produced by said method. A regenerative therapy composition comprising biological tissue in which a vascular system has been provided by said method. |
申请公布号 |
AU2014294233(A1) |
申请公布日期 |
2016.02.04 |
申请号 |
AU20140294233 |
申请日期 |
2014.07.15 |
申请人 |
PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY |
发明人 |
TAKEBE, TAKANORI;TANIGUCHI, HIDEKI;TAKAHASHI, YOSHINOBU |
分类号 |
C12N5/071;A01K67/027;A61L27/00;C07D499/21;G01N33/50 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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