| 主权项 |
1. A compound of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof: wherein: A1 is NR18, O, or S, (CH2)q, or —NH(CH2)q; —N(H)—N═C*—(CH2)mCH3 R1 is optionally substituted alkyl, optionally substituted aryl, optionally substituted pyridyl, optionally substituted pyrimidinyl, optionally substituted pyrazinyl, optionally substituted pyridazinyl, or triazinyl; dd-dd R2 is , optionally substituted aryl, optionally substituted pyridyl, optionally substituted pyrimidinyl, optionally substituted pyrazinyl, optionally substituted pyridazinyl, or triazinyl; R3 is H, OR4, NR5R6, NO2, SO2NH2, halo, optionally substituted alkyl, optionally substituted heteroalkyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted carbocycle, optionally substituted heterocycle, optionally substituted carboxyl, optionally substituted alkoxycarbonyl, or optionally substituted aryloxycarbonyl; R4, R5, and R6 are each independently H, halo, optionally substituted alkyl, optionally substituted heteroalkyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted carbocycle, or optionally substituted heterocycle; R18 is H, optionally substituted alkyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted heteroaryl, optionally substituted carbocycle, or optionally substituted heterocycle; C* is where R2 bonds with the group —N(H)—N═C*—(CH2)mCH3; m is 0-6; and q is 1-6. |
