发明名称 STABILIZED FORMULATIONS CONTAINING ANTI-INTERLEUKIN-6 RECEPTOR (IL-6R) ANTIBODIES
摘要 PROBLEM TO BE SOLVED: To provide pharmaceutical formulations comprising a human antibody that specifically binds to human interleukin-6 receptor (hIL-6R).SOLUTION: The pharmaceutical formulations contain, in addition to an anti-hIL-6R antibody, at least one amino acid, at least one sugar, and/or at least one non-ionic surfactant. The pharmaceutical formulations exhibit a substantial degree of antibody stability after storage for several months.SELECTED DRAWING: None
申请公布号 JP2016020371(A) 申请公布日期 2016.02.04
申请号 JP20150171642 申请日期 2015.09.01
申请人 REGENERON PHARMACEUTICALS INC 发明人 DANIEL B DIX;KENNETH S GRAHAM;DOUGLAS E KAMEN;SCOTT M WALSH
分类号 A61K39/395;A61K47/14;A61K47/18;A61K47/22;A61K47/26;A61K47/34;A61P25/00;A61P29/00 主分类号 A61K39/395
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