发明名称 |
STABILIZED FORMULATIONS CONTAINING ANTI-INTERLEUKIN-6 RECEPTOR (IL-6R) ANTIBODIES |
摘要 |
PROBLEM TO BE SOLVED: To provide pharmaceutical formulations comprising a human antibody that specifically binds to human interleukin-6 receptor (hIL-6R).SOLUTION: The pharmaceutical formulations contain, in addition to an anti-hIL-6R antibody, at least one amino acid, at least one sugar, and/or at least one non-ionic surfactant. The pharmaceutical formulations exhibit a substantial degree of antibody stability after storage for several months.SELECTED DRAWING: None |
申请公布号 |
JP2016020371(A) |
申请公布日期 |
2016.02.04 |
申请号 |
JP20150171642 |
申请日期 |
2015.09.01 |
申请人 |
REGENERON PHARMACEUTICALS INC |
发明人 |
DANIEL B DIX;KENNETH S GRAHAM;DOUGLAS E KAMEN;SCOTT M WALSH |
分类号 |
A61K39/395;A61K47/14;A61K47/18;A61K47/22;A61K47/26;A61K47/34;A61P25/00;A61P29/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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