发明名称 RADIOLABELED COMPOUNDS
摘要 The present invention relates to radiolabeled compounds of formula I;;wherein R1, R2, R3 and R4 are as defined herein.
申请公布号 US2016031878(A1) 申请公布日期 2016.02.04
申请号 US201514813293 申请日期 2015.07.30
申请人 Hoffmann-La Roche Inc. 发明人 BORRONI Edilio;FLOHR Alexander;GOBBI Luca;HARTUNG Thomas;HOAREAU Raphael;HONER Michael;MARTARELLO Laurent
分类号 C07D471/04;A61K51/04;C07B59/00 主分类号 C07D471/04
代理机构 代理人
主权项 1. A radiolabeled compound of formula I wherein R1 and R2 are independently selected from C1-7 alkyl, C1-7 haloalkyl, R1 and R2, together with the nitrogen atom to which they are attached, form heterocycloalkyl, R3 is C1-7 alkyl, R4 is hydrogen, C1-7 alkoxy or C1-7 haloalkoxy and wherein either R1, R2, R3 or R4 is labeled with a radionuclide selected from 3H, 11C and 18F.
地址 Little Falls NJ US
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