发明名称 |
ANTI-GCC ANTIBODY MOLECULES AND RELATED COMPOSITIONS AND METHODS |
摘要 |
Antibodies and antigen-binding fragments of antibodies that bind GCC are disclosed. In some embodiments, the antibodies are humanized, chimeric or human. Nucleic acids and vectors encoding the antibodies or portions thereof, recombinant cells that contain the nucleic acids, and compositions comprising the antibodies or antigen-binding fragments are also disclosed. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding |
申请公布号 |
US2016030595(A1) |
申请公布日期 |
2016.02.04 |
申请号 |
US201514879936 |
申请日期 |
2015.10.09 |
申请人 |
Thomas Jefferson University |
发明人 |
Waldman Scott A.;Magee Michael S.;Snook Adam E. |
分类号 |
A61K47/48;A61K51/10;A61K35/17;C07K16/40 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Philadelphia PA US |