| 发明名称 |
CONCENTRATED HUMAN IMMUNOGLOBULIN COMPOSITION |
| 摘要 |
A liquid pharmaceutical composition containing human immunoglobulin G, preferably at 230 g/l or higher. The composition, suitable for subcutaneous or intramuscular administration, can be used to treat various diseases, e.g., an antibody production defect and Kawasaki disease. |
| 申请公布号 |
US2016030563(A1) |
申请公布日期 |
2016.02.04 |
| 申请号 |
US201514879673 |
申请日期 |
2015.10.09 |
| 申请人 |
Laboratoire Francais Du Fractionnement Et Des Biotechnologies |
发明人 |
Huille Sylvain;Cohen-Tannoudji Laetitia;Arvis Florence;Paillard Alexandra |
| 分类号 |
A61K39/395;A61K9/00;A61K47/12;A61K47/26;C07K16/06;A61K47/18 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A liquid pharmaceutical composition obtained by the following process:
a. providing a human immunoglobulin G (IgG) preparation; b. adding to the preparation at least one surfactant and/or at least one amino acid; c. concentrating the IgG by ultrafiltration; and d. adding a surfactant identical to or different from the surfactant added in step b;in which the pharmaceutical composition obtained is at a pH between 4.2 and 5.5. |
| 地址 |
Les Ulis FR |
