| 发明名称 |
Purification and Purity Assessment of RNA Molecules Synthesized with Modified Nucleosides |
| 摘要 |
This invention provides purified preparations of an RNA, oligoribonucleotide, or polyribonucleotide comprising a modified nucleoside, and methods of assessing purity of purified preparations of an RNA, oligoribonucleotide, or polyribonucleotide comprising a modified nucleoside. |
| 申请公布号 |
US2016032316(A1) |
申请公布日期 |
2016.02.04 |
| 申请号 |
US201414776525 |
申请日期 |
2014.03.13 |
| 申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
Weissman Drew;Kariko Katalin |
| 分类号 |
C12N15/85;C07K14/505;C07K14/475;C12P19/34;C07H21/02 |
主分类号 |
C12N15/85 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A purified preparation of messenger RNA comprising a 1-methyl-pseudouridine residue. |
| 地址 |
Philadelphia PA US |
