| 摘要 |
Dye composition for keratinous fibers comprises an oxidation dye such as 3-amino pyrazolo-[1,5-a]-pyridine derivative (I) or its salts or solvates, in a medium. Dye composition for keratinous fibers comprises an oxidation dye such as 3-amino pyrazolo-[1,5-a]-pyridine derivative of formula (I) or its salts or solvates, in a medium. Z 1, Z 2simple covalent bond, -O- or -NR 6(R 7) p; p : 0-1; either R 6H or 1-6C alkyl (both when p is 0); or NR 6R 1, NR 6R 2T (when p is 0); or NR 6R 7cationic radical (when p is 1) (where R 6 and R 7 are alkyl); R 1, R 2H, 1-10C alkyl (optionally substituted and terminated with a heteroatorm O, N, Si, S, SO or SO 2, or a cation), halo, SO 3H or T; R, R aH or 1-6C alkyl (optionally substituted); either R 3-R 5H, OH, 1-6C alkoxy, 1-6C alkylthio, (monoalkyl)amino, 1-6C dialkyl (where the alkyls together with N can form T), 1-6C alkylcarbonyl (optionally substituted), -O-CO-R-, -CO-O-R, N-CO-R a, CO-NRR a, halo, -NHSO 3H-, 1-4C alkyl (optionally substituted) or optionally substituted carbonaceous ring; or R 3R 4, R 3R 5, R 4R 5optionally saturated ring cycle; T : 5-8 membered heterocycle, containing a heteroatom e.g. N, O, S, SO 2 or CO and the heterocycle optionally being cation and/or substituted by a cation; and X : anions complementary to the electronegativity of (I). Provided that Z 1 is -S-, -SO- or -SO 2-, when R 1 is methyl. Provided that at least one of Z 1 and Z 2 is different from a simple covalent bond. Provided that at least one of Z 1, R 1, Z 2 and R 2 is cationic. Provided that when Z 1 and Z 2, respectively, represent a covalent bond, then R 1 and R 2, respectively, are 1-6C alkylcarbonyl (optionally substituted), -O-CO-R, -CO-O-R, N-CO-R a or -CO-NRR a. Independent claims are included for: (1) dyeing of keratinous fibers comprising applying the composition on the keratinous fibers in the presence of an oxidizing agent to develop the desired color; (2) a device comprising compartments, where the first compartment contains the composition and the second compartment contains an oxidizing agent; (3) 3-amino pyrazolo-[1,5-a]-pyridine derivative (I); (4) preparation of (I) comprising reaction of pyridinium derivative of formula (II) with 1,1-bis-methylsulfanyl-2-nitro-ethene in the presence of dipotassium carbonate and dimethyl formamide to obtain a pyrazolopyridine derivative of formula (III), oxidation of (III) to obtain 3-nitro-2-(methyl sufanyl)-pyrazolopyridine derivative of formula (IV), reaction of (IV) with a hydride of formula (R 1Z 1H) to obtain 3-nitro-pyrazolopyridine derivative of formula (V) and reduction of (V ) to obtain (I); and (5) intermediate compounds (IV) and (V). Z' 2, R' 2-R' 5Z 2, R 2-R 5, respectively or their precursors. [Image]. |
