发明名称 PIPERIDINONE CARBOXAMIDE SPIROHYDANTOIN CGRP RECEPTOR ANTAGONISTS
摘要 The present invention is directed to piperidinone carboxamide spirohydantoin derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
申请公布号 EP2685826(B1) 申请公布日期 2016.02.03
申请号 EP20120760589 申请日期 2012.03.14
申请人 MERCK SHARP & DOHME CORP. 发明人 BELL, IAN, M.;BELARDI, JUSTIN
分类号 C07D487/10;A61K31/444 主分类号 C07D487/10
代理机构 代理人
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