| 发明名称 | Reovirus vaccines and methods of use therefor | ||
| 摘要 | The present invention provides for modified reoviruses that carry α-helical epitopes from a variety of pathogens, as well as methods of using such modified reoviruses to generate immune responses against those epitopes in hosts. | ||
| 申请公布号 | US9249195(B2) | 申请公布日期 | 2016.02.02 |
| 申请号 | US201113639564 | 申请日期 | 2011.04.04 |
| 申请人 | Vanderbilt University | 发明人 | Dermody Terence S.;Boehme Karl W.;Ikizler Mine;Wilson Gregory J.;Chappell James D. |
| 分类号 | C07K14/14;C07K14/005;A61K39/15;A61K39/21;A61K39/12;A61K39/00 | 主分类号 | C07K14/14 |
| 代理机构 | Parker Highlander PLLC | 代理人 | Parker Highlander PLLC |
| 主权项 | 1. A modified reovirus σ1 protein comprising a first α-helical antigenic epitope from a non-reovirus antigen inserted into an α-helical region of said protein. | ||
| 地址 | Nashville TN US | ||