发明名称 |
Compositions and method for treatment of ischemic neuronal reperfusion injury |
摘要 |
A method and composition for the treatment of ischemic neuronal reperfusion injury are provided. The composition can include a compound which is a combination of dantrolene and a residue of FMOC-valine. This composition can be used to provide a faster and higher CNS penetration than heretofore experienced with dantrolene. In another form, dantrolene may be formulated as a pro-drug, a pro-pro-drug and the like. |
申请公布号 |
US9248118(B2) |
申请公布日期 |
2016.02.02 |
申请号 |
US201514626126 |
申请日期 |
2015.02.19 |
申请人 |
Howard University |
发明人 |
Mangat Harpal S.;Karla Pradeep K. |
分类号 |
A61K31/4178;C07D405/12;A61K45/06;A61K38/05 |
主分类号 |
A61K31/4178 |
代理机构 |
Fitch Even Tabin & Flannery LLP |
代理人 |
Fitch Even Tabin & Flannery LLP |
主权项 |
1. A gas mask which includes at least one of a compound being deliverable to a wearer, the compound having at least one of the general formulas I, II and III |
地址 |
Washington DC US |