| 主权项 |
1. A functionalized dye comprising at least one chromophore and a color fastness moiety, wherein the chromophore is bound to the color fastness moiety by a linker, wherein said dye is a compound of formula Ia:
C-L-F (Ia), wherein C is a chromophore of formula IIg: wherein R7c is attached to linker L; R7a, R7b, R7d, R7e, R7f, R7g, R7h, R7i and R7j are each independently hydrogen, hydroxyl, alkyl, alkenyl, alkynyl, aryl, amino, alkylammonium, sulfonyl, carbonyl, carboxy, alkoxy, aryloxy, halogen, acyl, oximyl, hydrazinyl, —NO2, —CN, an heterocyclic moiety or thioether; L is a linker of formula (III):wherein
L covalently links the chromophore C via the left hand side of formula III to the color fastness moiety F via the right hand side of formula III; a, b, c, d, e, and f are each independently an integer from 0-2, provided that at least one of a, b, c, d, e and f is not 0; R40, R41, R42, R43, R44, R45, R46, R47, R48, R49, R50 and R51 are each independently absent or hydrogen; E is NR52 or NR53C═O; R52 and R53 are each independently hydrogen or alkyl; F is a color fastness moiety is of formula (Va):wherein
m, n, o, p, q and r are each independently an integer from 0-2, provided that at least one of m, n, o, p, q and r is not 0; R78, R79, R80, R81, R82, R83, R84, R85, R87, R88 and R89 are each independently hydrogen or absent; R86 is absent, hydrogen or hydroxyl; K is NR90, C(═O)NR92 or OC═O; W is NR95R96, CR97R98R99 or OR100; R90 and R92 are each independently hydrogen or alkyl; R95 is alkyl and R96 is hydrogen or alkyl, or R95 and R96, together with the nitrogen to which they are attached are linked to form an 4-8-membered heterocyclic ring comprising 1-3 heteroatoms; R97, R98, and R99 are independently selected from hydrogen, hydroxyl, alkyl, alkoxy, or heteroaryl; and R100 is hydrogen or alkyl; or a cosmetically acceptable salt thereof. |
