| 摘要 |
Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample. |
| 主权项 |
1. A biological sample processing device comprising:
a) a pipette comprising at least a first nozzle and a second nozzle; b) a detection station comprising an optical sensor; c) a cytometry station comprising an imaging device and a stage for receiving a microscopy cuvette, and d) a cartridge supporting multiple components comprising i) a biological sample and ii) at least a first, a second, and a third fluidically isolated assay unit, wherein the first assay unit and second assay unit each comprise a pipette tip; wherein the third assay unit comprises a microscopy cuvette configured to interface with the stage, and the third assay unit further comprises a first pipette interface and a second pipette interface, and wherein the pipette is configured to i) transfer at least a portion of the biological sample to the first assay unit, the second assay unit, and the third assay unit; ii) transfer the first and second assay units containing biological sample to the detection station; and iii) engage the third assay unit at the first pipette interface with the first nozzle and at the second pipette interface with the second nozzle, and, while the third assay unit is engaged with the first nozzle and second nozzle, transfer the third assay unit containing biological sample to the cytometry station. |
