| 摘要 |
There are provided compositions for inhibiting the growth of Gram-positive bacteria and Gram-negative bacteria, comprising a myeloperoxidase, glycine, a peroxide-producing oxidase, and at least one additional amino acid selected from the group consisting of D-isoleucine, L-tyrosine, beta alanine, D-valine, L-isoleucine, L-valine, L-aspartic acid, D-alanine methyl ester, L-leucine, L-alanine, L-glutamine, L-lysine, L-histidine, D-alanine, L-glutamic acid, L-serine, and L-proline, which amino acid works in combination with the myeloperoxidase, glycine, and oxidase to enhance the microbicidal activity of the myeloperoxidase, and wherein the composition comprises from 12.5 pg/ml to 5,000 pg/ml of myeloperoxidase, 1.25 mM to 500 mM of glycine and each amino acid, and from 4.2 U/ml to 500 U/ml of the peroxide-producing oxidase. |
