摘要 |
The invention relates to novel 5,6-disubstituted oxindole derivatives of formula (I) (see formula I) to pharmaceutical agents containing said components and to the use thereof for producing a medicament. In formula (I), R1 and R2 are independently of one another hydrogen, C1-C3-alkyl, C1-C3-fluoroalkyl, C1-C3-alkoxy, C1-C3-fluoroalkoxy, halogen or CN; R3 is hydrogen or C1-C4-alkyl; R4 is ethoxy, fluorinated ethoxy or isopropoxy; R5 is hydrogen or methyl; R6 is Br, Cl, F or CN; R7 is Cl, F or CN; R8 and R9 are independently of one another C1-C3-alkyl or C1-C3-fluoroalkyl; X1 is O, NH or CH2; X2 and X3 are N or CH, with the proviso that X2 and X3 are not simultaneously N; X4 is N or CH; a and b are independently of one another 0, 1 or 2; and m, n, o and p are independently of one another 1, 2 or 3. |
申请人 |
ABBOTT GMBH & CO. KG |
发明人 |
BRAJE, WILFRIED;OOST, THORSTEN;NETZ, ASTRID;WERNET, WOLFGANG;UNGER, LILIANE;HORNBERGER, WILFRIED;LUBISCH, WILFRIED |