发明名称 |
Method for producing poly-3-hydroxyalkanoic acid and agglomerates thereof |
摘要 |
When industrially separating and purifying poly-3-hydroxyalkanoic acid produced by a microorganism, to obtain poly-3-hydroxyalkanoic acid agglomerates having an arbitrary volume mean particle diameter with favorable productivity and with decreased amount of an organic solvent used is enabled while decreasing contaminants derived from constitutive components of cellular bodies. According to the present invention, agglomerates of poly-3-hydroxyalkanoic acid are obtained by adjusting the pH of an aqueous poly-3-hydroxyalkanoic acid suspension to fall within an acidic region. |
申请公布号 |
US9249258(B2) |
申请公布日期 |
2016.02.02 |
申请号 |
US200913133610 |
申请日期 |
2009.12.02 |
申请人 |
Kaneka Corporation |
发明人 |
Takita Masaki;Yanagita Yoshifumi |
分类号 |
C08G63/06;C08G63/88;C08G63/90;C08J3/14;C12P7/62 |
主分类号 |
C08G63/06 |
代理机构 |
Novak Druce Connolly Bove + Quigg LLP |
代理人 |
Novak Druce Connolly Bove + Quigg LLP |
主权项 |
1. A method for producing poly-3-hydroxyalkanoic acid agglomerates, the method comprising
culturing a microorganism having an ability to intracellularly produce poly-3-hydroxyalkanoic acid; purifying poly-3-hydroxyalkanoic acid in the absence of any organic solvent by degradation and/or removal of impurities to obtain an aqueous poly-3-hydroxyalkanoic acid suspension having an amount of organic nitrogen of not greater than 6,000 ppm per weight of the poly-3-hydroxyalkanoic acid, allowing poly-3-hydroxyalkanoic acid to be aggregated by adjusting the pH of the aqueous poly-3-hydroxyalkanoic acid suspension to fall within an acidic region after purifying poly-3-hydroxyalkanoic acid by degradation and/or removal of impurities to obtain poly-3-hydroxyalkanoic acid agglomerates. |
地址 |
Osaka JP |