Multilaminate backing construction

摘要

A novel backing construction for a transdermal drug delivery system is disclosed. In particular, the invention relates to a system and method for labeling a transdermal drug delivery system, wherein the backing layer contains a writable medium capable of inkless printing.

主权项

1. A method for transdermal administration of a drug, comprising:
providing a transdermal drug delivery device for application on skin comprising a multilaminate backing construction disposed away from the skin relative to a primary drug-containing reservoir layer when the device is applied to the skin, the primary drug-containing reservoir layer comprising a primary drug selected from the group consisting of a therapeutic agent and an antagonist, the backing construction comprising: (a) an outer layer comprising an embossable, writable and breathable material, (b) a multilaminate tie layer disposed on the skin proximal surface of the outer layer, wherein the tie layer comprises a secondary drug-containing reservoir layer comprising a secondary drug selected from the group consisting of an antagonist and a therapeutic agent, the secondary drug being different from the primary drug, and (c) a base layer disposed on the skin proximal surface of the tie layer; and applying the device to the skin.