发明名称 |
Phosphoinositide 3-kinase inhibitor with a zinc binding moiety |
摘要 |
The invention provides a compound of Formula I,;
Pharmaceutical compositions comprising such compounds and the use of such compounds in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. The instant application further relates to the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase. |
申请公布号 |
US9249156(B2) |
申请公布日期 |
2016.02.02 |
申请号 |
US201414197769 |
申请日期 |
2014.03.05 |
申请人 |
Curis, Inc. |
发明人 |
Cai Xiong;Zhai Haixiao;Lai Chengjung;Qian Changgeng;Bao Rudi |
分类号 |
C07D495/14;C07D239/70;C07D413/14;A61K31/535;C07D495/04 |
主分类号 |
C07D495/14 |
代理机构 |
Elmore Patent Law Group, P.C. |
代理人 |
Elmore Patent Law Group, P.C. ;Harlan Edgar W.;Elmore Carolyn S. |
主权项 |
1. A salt of a compound represented by the formula:wherein said salt is a benzenesulfonate salt or a methanesulfonate salt. |
地址 |
Lexington MA US |