发明名称 (4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL)-(7-FLUORO-1-(2-METHOXY-ETHYL)-4TRIFLUOROMETHOXY-1H-INDOL-3-YL)METHANONE AS AN INHIBITOR OF MAST CELL TRYPTASE
摘要 The present invention is directed to an indole benzylamine compound of formula I: useful as an inhibitor of tryptase. In addition, the present invention is directed to the use of the compound for treating a patient suffering from, or subject to, a physiological condition in need of amelioration by inhibition of tryptase, comprising administering to the patient of a therapeutically effective amount of the compound, and to a pharmaceutical composition comprising a pharmaceutically effective amount of the compound of formula I, and a pharmaceutically acceptable carrier.
申请公布号 SI2367812(T1) 申请公布日期 2016.01.29
申请号 SI20090031335T 申请日期 2009.08.20
申请人 SANOFI 发明人 CHOI-SLEDESKI YONG MI;CHOY NAKYEN;POLI GREGORY BERNARD;SHAY JOHN J. JR.;SHUM PATRICK WAI-KWOK;SLEDESKI ADAM W.
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