摘要 |
The present invention provides a method for the generation ofRa of pharmaceutically tolerable purity comprising: i) preparing a generator mixture comprisingAc,Th andRa; ii) loading said generator mixture onto a strong base anion exchange resin; iii) eluting saidRa from said strong base anion exchange resin using a first mineral acid in an alcoholic aqueous solution to give a first elutedRa solution; iv) loading the first elutedRa solution onto a strong acid cation exchange resin; and v) eluting theRa from said strong acid cation exchange resin using a second mineral acid in aqueous solution to provide a second eluted solution. The invention additionally provides products of corresponding purity and/or products obtained or obtainable by such a method. |