| 发明名称 |
JAK2 INHIBITORS AND THEIR USE FOR THE TREATMENT OF MYELOPROLIFERATIVE DISEASES AND CANCER |
| 摘要 |
The present invention provides compounds of formula (I) wherein R, X, Y are disclosed in the claims:and pharmaceutically acceptable salts thereof. The formula (I) compounds inhibit tyrosine kinase activity of JAK2, thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases. |
| 申请公布号 |
EA022488(B1) |
申请公布日期 |
2016.01.29 |
| 申请号 |
EA20120070373 |
申请日期 |
2010.09.02 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
PURANDARE ASHOK, V.;GREBINSKI JAMES, W.;HART AMY;INGHRIM JENNIFER;SCHROEDER GRETCHEN;WAN HONGHE |
| 分类号 |
C07D471/14;A61K31/437;A61P35/00 |
主分类号 |
C07D471/14 |
| 代理机构 |
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