GENOMICS-BASED ALERTING SYSTEMS

摘要

Alerting systems include mechanical chemical systems for analyzing a human DNA samples to produce a genomic data set representing genetic indicators or markers on alleles of interest including those as well SNPs associated with important trial traits disease and characteristics. A genome dataset is stored as a portion of a data a record having a one-to-one correspondence with membership in a membership database. A dynamic rule that provides a query engine with logic which can be executed against membership data stored in accordance with standardized database procedures to produce a genomic result set from which appropriate alerts may be formed in a computer apparatus. These alerts may be characterized as including multimedia information and they may be prefer to play conveyed to membership with whom the underlying data is associated.

主权项

1. A genomics-based alerting system comprising:
a genome scanner machine; a storage utility; a human-controlled rules generator; an analyzer; an alert module; and an electronic distribution system, said genome scanner comprises a DNA receiving port and is configured for receiving a human genomic DNA sample, isolating therefrom particular genetic features, and forming digital output encoding genome data relating to the isolated genetic features; said storage utility is configured for receiving the digital genome data from the genome scanner machine and storing the digital genome data in a membership database, which comprises the digital genome data and health-related factors of each of a plurality of members specifically configured such that there is a one-to-one correspondence between members, associated digital genome data, and health-related factors, wherein the health-related factors comprise at least one of lifestyle factors, metabolic measurements, family history, medical record data, and exercise regimen; said rules generator is configured for converting non-discrete conclusions of research studies relating to a presence or absence of particular genetic features into discrete, updatable and machine executable rules and algorithms, the rules and algorithms being updated in response to new research studies, wherein the rules generator is human controlled and comprises a user interface configured for enabling a human expert to manipulate the states and variables of prescribed template rules to arrive at the algorithms and rules, such that the algorithms and rules reflect the nature of the new research studies read by the human expert and such that the algorithms and rules are updated as new research studies are made available; said analyzer module configured for forming database queries in view of the new rules and algorithms to interrogate the membership database to identify members having genetic characteristics defined in each of the new rules and algorithms, and for outputting a result set in response to the database queries, wherein the database queries are scheduled to automatically run against the digital genome data whenever a new rule becomes available; said alert module is configured for receiving the result set and generating electronic reports in accordance with information received in the result set, wherein the electronic reports explain a circumstance relating to the conclusions of the research studies to at least one member having a genetic characteristic and a health-related factor identified in the new research studies, as defined in the new rules and algorithms; and said electronic distribution system is configured for receiving said electronic reports from the alert module and directing the electronic reports to at least one alert delivering email address associated with the at least one member, wherein the electronic report generated by the alert module is delivered automatically to all members having a genetic characteristic as identified in the new research studies and defined in the new rule.