| 摘要 |
PROBLEM TO BE SOLVED: To provide a 1,2-disubstituted heterocyclic compound which is inhibitor of phosphodiesterase 10, and a method of treating central nervous system disorders and the like using the compound.SOLUTION: The compounds are represented by the formulas (I), (II) and (III). (HET is a 5- or 6-membered heterocycle having a carbonyl group; W is halogen, cyano, nitro, amino, alkylamino, carboxy, or the like; X is substituted/unsubstituted alkyl, cycloalkyl, aryl, or the like; Y is a divalent linker group; and Z is heteroaryl.) |
