发明名称 |
Method and Pharmaceutical Composition for use in the Treatment and Prediction of Myocardial Infarction |
摘要 |
The present invention relates to a method for predicting the survival time of a patient suffering of myocardial infarction or the recurrence of a myocardial infarction in a patient who has suffered from a myocardial infarction comprising the steps consisting of i) determining the expression level of BAFF in a sample from said patient, ii) comparing said expression level with a predetermined reference value and iii) providing a good prognosis of the survival time or a low risk of the recurrence of a myocardial infarction when the expression level is lower than the predetermined reference value and a poor prognosis of the survival time or a high risk of the recurrence of a myocardial infarction when the expression level is higher than the predetermined reference value. |
申请公布号 |
US2016024218(A1) |
申请公布日期 |
2016.01.28 |
申请号 |
US201414776029 |
申请日期 |
2014.03.14 |
申请人 |
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) ;UNIVERSITÉ PARIS DESCARTES ;UNIVERSITÉ PIERRE ET MARIE CURIE - UPMC ;ASSISTANCE PUBLIQUEHÔPITAUX DE PARIS (APHP) |
发明人 |
Mallat Ziad;Tedgui Alain;Simon Tabassome;Danchin Nicolas |
分类号 |
C07K16/28;G01N33/68 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
1. A method for predicting the survival time of a patient suffering from myocardial infarction or the recurrence of a myocardial infarction in a patient who has suffered from a myocardial infarction comprising the steps of i) determining the expression level of B cell activating factor (BAFF) in a sample from said patient, ii) comparing said expression level with a predetermined reference value and iii) providing a good prognosis of the survival time or a low risk of the recurrence of a myocardial infarction when the expression level is lower than the predetermined reference value and a poor prognosis of the survival time or a high risk of the recurrence of a myocardial infarction when the expression level is higher than the predetermined reference value. |
地址 |
Paris FR |