发明名称 Method and Pharmaceutical Composition for use in the Treatment and Prediction of Myocardial Infarction
摘要 The present invention relates to a method for predicting the survival time of a patient suffering of myocardial infarction or the recurrence of a myocardial infarction in a patient who has suffered from a myocardial infarction comprising the steps consisting of i) determining the expression level of BAFF in a sample from said patient, ii) comparing said expression level with a predetermined reference value and iii) providing a good prognosis of the survival time or a low risk of the recurrence of a myocardial infarction when the expression level is lower than the predetermined reference value and a poor prognosis of the survival time or a high risk of the recurrence of a myocardial infarction when the expression level is higher than the predetermined reference value.
申请公布号 US2016024218(A1) 申请公布日期 2016.01.28
申请号 US201414776029 申请日期 2014.03.14
申请人 INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) ;UNIVERSITÉ PARIS DESCARTES ;UNIVERSITÉ PIERRE ET MARIE CURIE - UPMC ;ASSISTANCE PUBLIQUEHÔPITAUX DE PARIS (APHP) 发明人 Mallat Ziad;Tedgui Alain;Simon Tabassome;Danchin Nicolas
分类号 C07K16/28;G01N33/68 主分类号 C07K16/28
代理机构 代理人
主权项 1. A method for predicting the survival time of a patient suffering from myocardial infarction or the recurrence of a myocardial infarction in a patient who has suffered from a myocardial infarction comprising the steps of i) determining the expression level of B cell activating factor (BAFF) in a sample from said patient, ii) comparing said expression level with a predetermined reference value and iii) providing a good prognosis of the survival time or a low risk of the recurrence of a myocardial infarction when the expression level is lower than the predetermined reference value and a poor prognosis of the survival time or a high risk of the recurrence of a myocardial infarction when the expression level is higher than the predetermined reference value.
地址 Paris FR