| 发明名称 |
COMPOSITIONS AND METHODS FOR MEK INHIBITOR COMBINATION THERAPY IN THE TREATMENT OF CANCER |
| 摘要 |
<p>Combined administration of a hypoxia-activated prodrug, such as TH 302, and a MEK kinase inhibitor, such as pimasertib, are efficacious in the treatment of cancer including pancreatic cancer.</p> |
| 申请公布号 |
WO2016014390(A1) |
申请公布日期 |
2016.01.28 |
| 申请号 |
WO2015US41100 |
申请日期 |
2015.07.20 |
| 申请人 |
MERCK PATENT GMBH;GOODSTAL, SAMANTHA A.;ELENBAAS, BRIAN A.;MA, JIANGUO |
发明人 |
GOODSTAL, SAMANTHA A.;ELENBAAS, BRIAN A.;MA, JIANGUO |
| 分类号 |
A61K45/06;A61K31/455;A61K31/675;A61P35/00 |
主分类号 |
A61K45/06 |
| 代理机构 |
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代理人 |
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