AUTOMATED IMAGING AND ANALYSIS OF THE HEMAGGLUTINATION INHIBITION ASSAY (HAI)

摘要

A system and method provide for high through put determination of agglutination states. The system includes a rotating table and multiple plate tilting stations. The system also includes one or more optical paths positioned to image entire plate arrays in tilted and/or untilted configurations. The system preferably includes image analysis software to analyze an image of an array of test wells and determine an agglutination state of each well based on the image analysis.

主权项

1. An method for determining functional binding activity of an antibody, comprising:
preparing a sample consisting of an agglutinating factor and said antibody; adding a target object to said sample under conditions permitting agglutination of said target object by said agglutinating factor; preparing an image of said sample with said target object added; processing said image in a programmed processing device to determine agglutination of said target object.