| 发明名称 |
METHOD OF TREATING PLEURAL ABNORMALITY |
| 摘要 |
The invention relates to a method of treating pleural abnormalities in a subject in need thereof, comprising the steps of: (a) attaching a biodegradable polymeric membrane onto a pleural wound to elicit fibronectin from fibroblasts to cause fibrous adhesion; and (b) securing the membrane with securement products, including sutures, staples, and sealants. The present invention also relates to a biodegradable adhesion membrane used for treating pleural abnormalities, comprising: a biodegradable base material selected from the group consisting of polycaprolactone (PCL), polylactic acid or polylactide (PLA), polyhydroxybutyrate (PHB), poly(ethylene adipate), poly(butylene adipate) (PBA), chitosan, hyaluronic acid, and polyglycolic acid (PGA); wherein the thickness of the membrane is 0.1-1 mm. |
| 申请公布号 |
US2016022878(A1) |
申请公布日期 |
2016.01.28 |
| 申请号 |
US201514805877 |
申请日期 |
2015.07.22 |
| 申请人 |
National Taiwan University |
发明人 |
Young Tai-Horng;Chen Jin-Shing;Lai Hong-Shiee;Chen Ke-Cheng;Chou Ya-Shuan;Lin Yong-Chong;Hsieh Hao-Ying;Chang Hsu-Hsien |
| 分类号 |
A61L31/06;A61L31/04;A61L31/16;A61B17/00;A61L31/14 |
主分类号 |
A61L31/06 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating pleural abnormalities in a subject in need thereof, comprising the steps of:
(a) attaching a biodegradable polymeric membrane onto a pleural wound to elicit fibronectin from fibroblasts to cause fibrous adhesion; and (b) securing the membrane with securement products, including sutures, staples, and sealants. |
| 地址 |
Taipei TW |
