| 发明名称 |
CHELATED DRUG DELIVERY SYSTEMS |
| 摘要 |
The present invention provides drug delivery compositions that allow for immediate and/or sustained release of a therapeutic agent contained within the system. The present invention also provides drug delivery compositions that preserve the stability of the therapeutic agent contained within during the sustained release. The present invention further provides a method of treating, ameliorating, or preventing an inflammation-related disease or disorder in a subject using the compositions of the invention. |
| 申请公布号 |
US2016022707(A1) |
申请公布日期 |
2016.01.28 |
| 申请号 |
US201414773883 |
申请日期 |
2014.03.14 |
| 申请人 |
DREXEL UNIVERSITY |
发明人 |
Zhong Yinghui;Zhang Zhiling |
| 分类号 |
A61K31/65;A61K31/496;A61K9/00;A61K47/48;A61K9/14 |
主分类号 |
A61K31/65 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising a therapeutic agent or a salt thereof, a polyelectrolyte and a polyvalent metal ion,
wherein the therapeutic agent chelates at least a fraction of the polyvalent metal ion, and wherein the polyelectrolyte comprises a polyanion, a predominantly polyanionic polyampholyte, or any combinations thereof. |
| 地址 |
Philadelphia PA US |
