摘要 |
In accordance with this invention a novel pharmaceutical product containing efavirenz, emtricitabine and tenofovir DF are provided as a multicomponent unitary oral dosage form, component 1 comprising tenofovir DF (and, optionally, emtricitabine) and component 2 comprising efavirenz, wherein components 1 and 2 are in a stabilizing configuration. In preferred embodiments component 1 is made by dry granulation. |
申请人 |
Bristol-Myers Squibb & Gilead Sciences, LLC |
发明人 |
DAHL, Terrence, C.;Hussain, Munir, A.;Lipper, Robert, A.;Jerzewski, Robert, L.;MENNING, Mark, M.;OLIYAI, Reza;YANG, Taiyin |