CONTROL OF pH IN AQUEOUS UREA-CONTAINING SOLUTIONS UTILIZING AMINO ACID-CONTAINING COMPOSITIONS

摘要

Aqueous calibration or quality control reagents that include urea are disclosed; the reagents may further include at least one amino acid-containing composition to provide pH stability thereto. Methods of production and use thereof are also disclosed.

主权项

1. A composition comprising an aqueous quality control or calibration reagent disposed in a closed system, the composition comprising:
urea present in a concentration in a range of from about 0.1 mM to about 150 mM; at least one buffer; and at least one amino acid-containing composition having at least one available primary or secondary amine, the at least one amino acid-containing composition being present in a sufficient amount so that the pH of the aqueous quality control or calibration reagent varies by +/−1.0 or less of the original pH following storage of the composition.