NUCLEIC ACID BINDING PROTEINS AND USES THEREOF

摘要

Compositions, systems and methods employing nucleic acid binding proteins for use in the regulation and/or modulation of nucleic acid based reactions, including transcription, translation, modification, digestion, and hybridization reactions. Such compositions are employed in controlling a variety of different reaction types involving nucleic acids.

主权项

1. A method of controlling a reaction with a nucleic acid, comprising:
providing the nucleic acid comprising at least one uracil containing nucleotide; providing a nucleic acid binding protein with specificity for binding uracil containing nucleic acids in contact with the nucleic acid, under conditions whereby the nucleic acid binding protein binds to a portion of the nucleic acid comprising the uracil containing nucleotide, whereby binding of the nucleic acid protein to the nucleic acid at least partially blocks the reaction with the nucleic acid.