| 主权项 |
1. A compound or salt thereof, said compound having a general formula selected from (I), (II), (III) or (IV):where
R1, R3, R4, or R5 is a linkage chemistry which provides a terminal functional moiety selected from the group consisting of protected or unprotected sulfhydryl moieties, protected or unprotected amine moieties, primary amine-reactive moieties, sulfhydryl-reactive moieties, photoreactive moieties, carboxyl-reactive moieties, arginine-reactive moieties, and carbonyl-reactive moieties; each Z is independently optionally substituted C1-4 alkyl, C1-4 alkoxy, N, O, S, and aryl, wherein substitution(s), when present, may be independently selected from the group consisting of C1-6 alkyl straight or branched chain, benzyl, halogen, trihalomethyl, C1-6 alkoxy, —NO2, —NH2, —OH, ═O, —COOR′ where R′ is H or lower alkyl, —CH2OH, and —CONH2, and where Z is preferably O, S, N, NH, CH3, CH2, CH, CHF or CF2, and where Z is most preferably —C(O)—, —N(H)— or —O—. each Y is independently selected from the group consisting of wherein each R2 is independently optionally substituted C1-4 alkyl, C1-4 alkoxy, OH, N, O, S, and aryl, wherein substitution(s), when present, may be independently selected from the group consisting of C1-6 alkyl straight or branched chain, benzyl, halogen, trihalomethyl, C1-6 alkoxy, —NO2, —NH2, —OH, ═O, —COOR′ where R′ is H or lower alkyl, —CH2OH, and —CONH2, and where each R2 is preferably CH3, CF3, CHF2, CH2F or NH2; and each X is H or together form a covalent bond. |
