Prostate-associated antigens and vaccine-based immunotherapy regimens
摘要
The present disclosure provides (a) isolated immunogenic PAA polypeptides; (b) isolated nucleic acid molecules encoding immunogenic PAA polypeptides; (c) vaccine compositions comprising an immunogenic PAA polypeptide or an isolated nucleic acid molecule encoding an immunogenic PAA polypeptide; (d) methods relating to uses of the polypeptides, nucleic acid molecules, and compositions; and (e) vaccine-based immunotherapy regimens which involve co-administration of a vaccine in combination with an immune-suppressive-cell inhibitor and an immune-effector-cell enhancer.
申请公布号
AU2013255511(B2)
申请公布日期
2016.01.28
申请号
AU20130255511
申请日期
2013.04.29
申请人
PFIZER INC.
发明人
BINDER, JOSEPH JOHN;CHO, HELEN KIM;DERMYER, MICHAEL ROBERT;JOOSS, KARIN UTE;PIERCE, BRIAN GREGORY;TAN, JOYCE TSI;TSAI, VAN TO