| 发明名称 |
METHOD FOR DEBLOCKING OF LABELED OLIGONUCLEOTIDES |
| 摘要 |
The invention relates to a process for deblocking substantially a blocked, detectably labeled oligonucleotide by contacting the blocked detectably labeled oligonucleotide with an effective amount of a nucleophilic amino compound under conditions that result in substantial deblocking of the oligonucleotide, thereby giving the substantially deblocked oligonucleotide. |
| 申请公布号 |
US2016024138(A1) |
申请公布日期 |
2016.01.28 |
| 申请号 |
US201514748930 |
申请日期 |
2015.06.24 |
| 申请人 |
LIFE TECHNOLOGIES CORPORATION |
发明人 |
GEBEYEHU Gulilat;Pires Richard |
| 分类号 |
C07H21/00 |
主分类号 |
C07H21/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A process for deblocking substantially a blocked, detectably labeled oligonucleotide comprising contacting the blocked detectably labeled oligonucleotide with an effective amount of a nucleophilic amino compound under conditions that result in the deblocking of the oligonucleotide, thereby giving the substantially deblocked oligonucleotide. |
| 地址 |
Carlsbad CA US |
