发明名称 |
PHAGE RESISTANT LACTIC ACID BACTERIA |
摘要 |
The present invention provides a method for the construction of a bacteriophage- insensitive mutant of a Streptococcus thermophilus parent strain whereby the bacteriophage insensitivity is not based on the CRISPR resistance mechanism but based on another mechanism. The method provides a protocol by which this can be achieved by inactivating one or more of the CRISPR systems present in a given strain. The invention also provides the bacteriophage-insensitive mutants as well as their use in a process for making a dairy product. |
申请公布号 |
WO2016012552(A1) |
申请公布日期 |
2016.01.28 |
申请号 |
WO2015EP66910 |
申请日期 |
2015.07.23 |
申请人 |
DSM IP ASSETS B.V. |
发明人 |
KOUWEN, ROELOF HENDRIK MATTHIJS;HANEMAAIJER, LAURENS LEENDERT;VAN SINDEREN, DOUWE;MCDONNELL, BRIAN;MAHONY, JENNIFER |
分类号 |
C12N1/20;A23C9/123;A23C19/032;C12N1/36 |
主分类号 |
C12N1/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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