Ocular Formulations for Drug-Delivery to the Posterior Segment of the Eye

摘要

The present invention relates to topical formulations comprising a compound of the following formula:;;for treating ocular neovascularization. The Compound-I is present in a solution or a suspension in about 0.005% to about 5.0% w/v, such that the solution or suspension delivers the compound at the posterior segment of the eye for inhibiting VEGF in the retina and/or the choroid.

主权项

1. A topical ocular formulation, comprising:
a. an active agent of Formula II:or a pharmaceutically acceptable salt thereof, and
b. pharmaceutically acceptable excipients;wherein the active agent or the pharmaceutically acceptable salt thereof is present in about 0.005% to about 5.0% w/v such that the formulation forms a solution or a suspension.