ON-BODY MICROSENSOR FOR BIOMONITORING

摘要

A microsensor and method of manufacture for a microsensor, comprising an array of filaments, wherein each filament of the array of filaments comprises a substrate and a conductive layer coupled to the substrate and configured to facilitate analyte detection. Each filament of the array of filaments can further comprise an insulating layer configured to isolate regions defined by the conductive layer for analyte detection, a sensing layer coupled to the conductive layer, configured to enable transduction of an ionic concentration to an electronic voltage, and a selective coating coupled to the sensing layer, configured to facilitate detection of specific target analytes/ions. The microsensor facilitates detection of at least one analyte present in a body fluid of a user interfacing with the microsensor.

主权项

1. A sensor for sensing analytes present in a body fluid of a user, the sensor comprising:
a substrate; and a filament including:
a substrate core including:
a base end coupled to the substrate,a columnar protrusion having a proximal portion coupled to the base end and a distal portion, anda tip region coupled to the distal portion of the columnar protrusion and configured to provide access to the body fluid of the user;a conductive layer, isolated to the tip region of the substrate core and away from the base end as an active region that enables transmission of electronic signals generated upon detection of an analyte within the body fluid;an insulating layer surrounding the substrate core and exposing a portion of the conductive layer, thereby defining a boundary of the active region; anda sensing layer, in communication with the active region, configured for at least one of amperometric sensing and potentiometric sensing of the analyte.