TRIFLUORMETHYLOXAZINE AMIDINES AS BACE1 INHIBITORS
摘要
<p>The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.</p>
申请公布号
WO2016012384(A1)
申请公布日期
2016.01.28
申请号
WO2015EP66505
申请日期
2015.07.20
申请人
F. HOFFMANN-LA ROCHE AG;HOFFMANN-LA ROCHE INC.;SIENA BIOTECH S.P.A.
发明人
DOLENTE, COSIMO;BARTELS, BJOERN;GUBA, WOLFGANG;HAAP, WOLFGANG;OBST SANDER, ULRIKE;PETERS, JENS-UWE;ROGERS-EVANS, MARK;WOLTERING, THOMAS
