COMPOSITIONS AND METHODS FOR TREATING DISEASE STATES ASSOCIATED WITH ACTIVATED T CELLS AND/OR B CELLS

摘要

Disclosed are combination therapies and related compositions that may contain one or more of a p53 potentiating agent, a DNA-damaging agent, an agent that inhibits cell cycle check point, and a pharmaceutically acceptable carrier. Also disclosed are methods of using such compositions for the treatment of conditions related to T cell and/or B cell activation in subjects in need of such treatment.

主权项

1. A composition comprising an agent selected from a p53 potentiating agent, a DNA-damaging agent, a DNA repair inhibitor/cell cycle checkpoint inhibitor, and combinations thereof, and a pharmaceutically acceptable carrier.