发明名称 DPP IV INHIBITOR FORMULATIONS
摘要 The present invention relates to pharmaceutical compositions of DPP IV inhibitors with an amino group, their preparation and their use to treat diabetes mellitus.
申请公布号 US2016022687(A1) 申请公布日期 2016.01.28
申请号 US201514877019 申请日期 2015.10.07
申请人 Boehringer Ingelheim International GmbH 发明人 KOHLRAUSCH Anja;ROMER Patrick;SEIFFERT Gerd
分类号 A61K31/522;A61K9/28;A61K9/20;A61K9/00 主分类号 A61K31/522
代理机构 代理人
主权项 1. A pharmaceutical composition comprising as an active ingredient a DPP IV inhibitor compound of formulain an amount of 0.5 mg, 1 mg, 2.5 mg, 5 mg or 10 mg, or a salt thereof, a first diluent, a second diluent, a binder, a disintegrant and a lubricant, wherein the first diluent is mannitol, the second diluent is pregelatinized starch, the binder is copovidone, the disintegrant is corn starch, and the lubricant is magnesium stearate; and wherein the DPP IV inhibitor compound is present in an amount 0.5-20% based on the total weight of DPP IV inhibitor compound, first diluent, second diluent, binder, disintegrant and lubricant.
地址 Ingelheim am Rhein DE
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