| 发明名称 |
Antibacterial Phage, Phage Peptides and Methods of Use Thereof |
| 摘要 |
The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophages F1245/05, F168/08, F170/08, F770/05, F197/08, F86/06, F87s/06 and F91a/06, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophages and/or isolated polypeptides and methods for the treatment and prevention of bacterial infection, either alone or in combination with other antibacterial therapies, e.g., antibiotics or other phage therapies. |
| 申请公布号 |
US2016022747(A1) |
申请公布日期 |
2016.01.28 |
| 申请号 |
US201514852112 |
申请日期 |
2015.09.11 |
| 申请人 |
TECHNOPHAGE, INVESTIGACAO E DESENVOLVIMENTO EM BIOTECNOLOGIA, SA ;TECNIFAR - INDUSTRIA TECNICA FARMACEUTICA, S.A. |
发明人 |
Da Costa Garcia Miguel Angelo;Sousa De Sao Jose Carlos Jorge;Rodrigues Leandro Clara Isabel;Dias Antunes Marcal Da Silva Filipa Maria Rodrigues Pardal;Ferreira Llorente Grancho Lourenco Sara |
| 分类号 |
A61K35/76;A61K9/00;C12N7/00 |
主分类号 |
A61K35/76 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating or reducing the incidence of an Acinetobacter baumanni bacterial infection in a subject in need thereof, said method comprising administering to said subject an effective amount of a pharmaceutical composition comprising a purified bacteriophage having a nucleic acid sequence of SEQ ID NO:760 and a pharmaceutically acceptable carrier. |
| 地址 |
LISBOA PT |
