| 发明名称 |
USE OF INHIBITORS OF MTOR TO IMPROVE VASCULAR FUNCTIONS IN APOE4 CARRIERS |
| 摘要 |
Disclosed are methods and compositions for preventing cerebrovascular function dysfunction in a patient who has been identified as an ApoE4 carrier. The disclosed methods and compositions include rapamycin, a rapamycin analog, or another such inhibitor of the target of rapamycin (TOR). |
| 申请公布号 |
US2016022649(A1) |
申请公布日期 |
2016.01.28 |
| 申请号 |
US201414775364 |
申请日期 |
2014.03.14 |
| 申请人 |
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
LIN Ai-Ling;RICHARDSON Arlan;GALVAN Veronica;FOX Peter;AUSTAD Steven;FISCHER Kathleen |
| 分类号 |
A61K31/436;A61K9/51;A23L1/30;A61K45/06 |
主分类号 |
A61K31/436 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for preventing cerebrovascular dysfunction in a patient comprising administering an effective amount of a composition comprising rapamycin or an analog thereof to a patient who has been identified as an ApoE4 carrier. |
| 地址 |
Austin TX US |
