| 发明名称 |
TMPRSS6 IRNA COMPOSITIONS AND METHODS OF USE THEREOF |
| 摘要 |
The invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the TMPRSS6 gene, and methods of using such RNAi agents to inhibit expression of TMPRSS6 and methods of treating subjects having a TMPRSS6 associated disorder, e.g., an iron overload associated disorder, such as &bgr;-thalassemia or hemochromatosis. |
| 申请公布号 |
SG11201510565T(A) |
申请公布日期 |
2016.01.28 |
| 申请号 |
SGT11201510565 |
申请日期 |
2014.05.22 |
| 申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
BUTLER, JAMES;BETTENCOURT, BRIAN;RAJEEV, KALLANTHOTTATHIL, G.;MAIER, MARTIN;CHARISSE, KLAUS |
| 分类号 |
C12N15/113;A61K31/713;C12N9/64 |
主分类号 |
C12N15/113 |
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