AN HIV-1 LATENCY MODEL FOR HIGH THROUGHPUT SCREENING
摘要
<p>Isolated, latently infected T cell lines are provided that can be utilized in high throughput screening to discover compounds capable of activating HIV-I. The T cell lines harbor a latent HIV-I derived vector pro virus, which upon activation expresses a marker for late viral gene expression due to the insertion of the marker gene in the position of HIV-I envelope.</p>
申请公布号
EP1963495(B1)
申请公布日期
2016.01.27
申请号
EP20060844574
申请日期
2006.11.27
申请人
UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
发明人
DOUGHERTY, JOSEPH, P.;MICHEVA-VITEVA, SOFIYA;PELTZ, STUART, W.;RON, YACOV;PACCHIA, ANNMARIE, L.