摘要 |
The present invention provides oligopeptides, in particular, Ang-(1-7) derivatives, and methods for using and producing the same. In one particular embodiment, oligopeptides of the invention have higher blood-brain barrier penetration and/or in vivo half-life compared to the native Ang-(1-7), thereby allowing oligopeptides of the invention to be used in a wide variety of clinical applications including in treatment of cognitive dysfunction and/of impairment. |
申请人 |
ARIZONA BOARD OF REGENTS FOR THE UNIVERSITY OF ARIZONA;HAY, MEREDITH;KONHILAS, JOHN;POLT, ROBIN, L. |
发明人 |
HAY, MEREDITH;KONHILAS, JOHN;POLT, ROBIN, L. |