发明名称 |
METHOD OF PRODUCING SERUM-FREE INSULIN-FREE FACTOR VII |
摘要 |
The invention provides methods and compositions for producing recombinant human factor VII (FVII) comprising obtaining a Chinese Hamster Ovary (CHO) cell line that expresses recombinant human FVII, culturing said CHO cell in serum-free media that lacks insulin wherein the production of said FVII in said CHO cell is comparable to the production of FVII in the presence of insulin. |
申请公布号 |
EP2977461(A1) |
申请公布日期 |
2016.01.27 |
申请号 |
EP20150169975 |
申请日期 |
2009.11.05 |
申请人 |
BAXALTA INCORPORATED;BAXALTA GMBH |
发明人 |
VON FIRCKS, SIMONE;ELMER, RUTH;DR. REITER, MANFRED |
分类号 |
C12P21/04;C07K14/745 |
主分类号 |
C12P21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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